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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LENG8 All Species: 18.79
Human Site: T521 Identified Species: 37.58
UniProt: Q96PV6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96PV6 NP_443157.1 779 86129 T521 V G T C P D I T K H Y L R L T
Chimpanzee Pan troglodytes XP_001174961 779 86160 T521 V G T C P D I T K H Y L R L T
Rhesus Macaque Macaca mulatta XP_001084592 751 82765 V502 D W Q E L Q I V G T C P D I T
Dog Lupus familis XP_533588 866 95014 T553 V G T C P D I T K H Y L R L T
Cat Felis silvestris
Mouse Mus musculus Q8CBY3 785 86748 H521 A A R F Q H G H S R R L R L E
Rat Rattus norvegicus NP_001032879 846 93215 T559 V G T C P D I T K H Y L R L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521626 835 91481 T576 V G T C P D I T K H Y L R L T
Chicken Gallus gallus
Frog Xenopus laevis Q32NW2 800 90307 G552 W D E I K I V G N S Q D I T K
Zebra Danio Brachydanio rerio A4QNR8 839 92784 G591 W D D C P I V G T C Q D I T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609459 874 99101 G569 A A R F S Q Q G S S S A K K S
Honey Bee Apis mellifera XP_001121422 801 90250 T528 R A A R F N D T I S R T V S N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190105 1466 163799 W1221 V G T S Q E E W K Q Y L R L T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 85.4 80.1 N.A. 86.3 81.3 N.A. 71.2 N.A. 59.2 48.7 N.A. 28.7 33.5 N.A. 24.4
Protein Similarity: 100 99.4 87.2 83.7 N.A. 89.5 84.5 N.A. 77.7 N.A. 70.3 58.8 N.A. 44.1 46.8 N.A. 33
P-Site Identity: 100 100 13.3 100 N.A. 20 100 N.A. 100 N.A. 0 13.3 N.A. 0 6.6 N.A. 60
P-Site Similarity: 100 100 20 100 N.A. 20 100 N.A. 100 N.A. 6.6 20 N.A. 13.3 13.3 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 25 9 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 50 0 0 0 0 0 9 9 0 0 0 0 % C
% Asp: 9 17 9 0 0 42 9 0 0 0 0 17 9 0 0 % D
% Glu: 0 0 9 9 0 9 9 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 17 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 0 0 0 0 9 25 9 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 9 0 42 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 17 50 0 9 0 0 0 17 9 0 % I
% Lys: 0 0 0 0 9 0 0 0 50 0 0 0 9 9 17 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 0 59 0 59 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 50 0 0 0 0 0 0 9 0 0 0 % P
% Gln: 0 0 9 0 17 17 9 0 0 9 17 0 0 0 0 % Q
% Arg: 9 0 17 9 0 0 0 0 0 9 17 0 59 0 0 % R
% Ser: 0 0 0 9 9 0 0 0 17 25 9 0 0 9 9 % S
% Thr: 0 0 50 0 0 0 0 50 9 9 0 9 0 17 59 % T
% Val: 50 0 0 0 0 0 17 9 0 0 0 0 9 0 0 % V
% Trp: 17 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _